Creative Proteomics’s Metabolomics Solution Supports Metabolite Analysis of Gut Microbiota 1
Creative Proteomics’s metabolomics services help researchers quantitatively and qualitatively analyze all metabolites of a certain biological component or cell under specific physiological or pathological conditions. These services can be applied to early disease diagnosis, drug target discovery, and disease mechanism research.

New York, USA – May 21, 2021 – Creative Proteomics, an experienced service provider in providing professional and high-quality services for academic research institutes and the pharmaceutical industry, has supported professional multi-omics service for worldwide customers in more than 50 countries and regions. Metabolomics services help researchers quantitatively and qualitatively analyze all metabolites of a certain biological component or cell under specific physiological or pathological conditions. These services can be applied to early disease diagnosis, drug target discovery, and disease mechanism research.

Creative Proteomics’s Metabolomics Solution Supports Metabolite Analysis of Gut Microbiota 2

Metabolomics mainly includes untargeted metabolomics and targeted metabolomics. Targeted metabolomics is used to determine the absolute concentration of targeted metabolites in a sample. Untargeted metabolomics is mainly used for qualitative analysis and relative quantification of different metabolites in sample groups.

The gut microbiome is involved in the regulation of various metabolic pathways in the host. It generates and releases metabolites that play a vital role in host metabolism, signaling, and immunity. Microbial metabolomics can reveal the key metabolites of the intestinal microbiome involved in the changes of host pathophysiology, providing clues for studying the mechanism of the microbiome – host interaction.

Creative Proteomics has extensive experience in providing advanced metabolomics services and can handle various types of samples, such as blood, urine, tissues, etc. In a collaboration with a research group in the Department of Internal Medicine, Yale University School of Medicine, Creative Proteomics provides untargeted metabolomics services to study the influence of PIXR abrogation on the composition of tick gut microbiota. UHPLC-QTOF-MS (Agilent 1290) and a UHPLC and AB QTOF 5600 (ACQUITY UHPLC) technology platforms were used to analyze the composition of the gut metabolome of ticks. After processing the raw data obtained from the mass spectrum, PCA, OPLS-DA, and t-test analysis were performed to determine the metabolites that are differentially expressed.

“Our specialized service is designed to provide a versatile and reliable metabolomics analysis. We have advanced equipment, professional metabolomics, and a bioinformatics team to ensure the quality of our service. Over the past ten years, Creative Proteomics has helped clients complete hundreds of projects, from project design and conducting experiments to the result interpretation and bioinformatics analysis,” stated Creative Proteomics’s executive VP.

About Creative Proteomics

Creative Proteomics has gradually grown into an integrated service provider with targeted metabolomics and untargeted metabolomics analysis services to researchers in pharmaceutical, biotechnology, agriculture, and nutrition industries, as well as academic and government organizations. With a continued focus on quality, Creative Proteomics is proud to satisfy our worldwide clients’ needs.

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